Ramona Trebbien

Ramona Trebbien

Kontakt

Ramona Trebbien, Seniorforsker, Virus & Mikrobiologisk Specialdiagnostik / Virus Overvågning og Forskning
T. 32683591 @. ratr@ssi.dk

Forskningsområder

Influenzavirus evolution i forhold til; patogenicitet, antiviral resistens, værtsfaktorer, receptorbinding, effekten på antigenicitet blandt andet i relation til vaccineeffektivitet mv. 

Antistofrespons mod influenzavirus efter vaccination og infektion i blandt andet særlige patientgrupper. 

Mekanismer bag zoonotisk transmission af influenzavirus mellem forskellige værter. 

Evolution og sygdomsbyrde af respiratorisk syncytial virus (RSV).

Ansvarsområder

Ansvarlig for det Nationale Influenza Center for WHO/Det nationale referencelaboratorium for influenza (link), med varetagelse af den nationale virologiske overvågning af influenzavirus samt respiratorisk syncytial virus (RSV). 

Publikationer

  • Rondy M, Kissling E, Emborg HD, Gherasim A, Pebody R, Trebbien R, Pozo F, Larrauri A, McMenamin J, Valenciano M, I-Move/I-Move Group. Interim 2017/18 influenza seasonal vaccine effectiveness: combined results from five European studies. Euro Surveill. 2018 Mar;23(9). doi: 10.2807/1560-7917.ES.2018.23.9.18-00086.
  • Trebbien R, Christiansen CB, Fischer TK. Antiviral resistance due to deletion in the neuraminidase gene and defective interfering-like viral polymerase basic 2 RNA of influenza A virus subtype H3N2. J Clin Virol. 2018 Feb 11;102:1-6. doi: 10.1016/j.jcv.2018.02.005. [Epub ahead of print]
  • Jepsen*, MT, Trebbien*, R., Emborg, HD, Krause, TG, Schønning, K, Voldstedlund, M, Nielsen, J, Fischer, TK. Incidence and seasonality of respiratory syncytial virus hospitalizations in young children in Denmark, 2010 to 2015. Accepted for publication in Eurosurveillance 2017.*Shared first authorship.
  • Trebbien R, Fischer TK, Krause TG, Nielsen L, Nielsen XC, Weinreich LS, Lis-Tønder J, Skov MN, Christiansen CB, Emborg HD. Changes in genetically drifted H3N2 influenza A viruses and vaccine effectiveness in adults 65 years and older during the 2016/17 season in Denmark. J Clin Virol. 2017 Jun 29;94:1-7. doi: 10.1016/j.jcv.2017.06.007.
  • Baratelli M, Pedersen LE, Trebbien R, Larsen LE, Jungersen G, Blanco E, Nielsen J, Montoya M. Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs. J Gen Virol. 2017 May;98(5):895-899. doi: 10.1099/jgv.0.000748. Epub 2017 May 30.