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in vitro and in vivo testing of antimicrobial compounds

in vitro evaluation of antimicrobials

  • Determination of minimum inhibitory concentrations (MIC) by broth dilution and agar dilution
  • Time kill activity
  • High throughput screening pf growth inhibition
  • Serum protein binding by ultrafiltration

in vitro models

  • in vitro urinary tract infection model
  • in vitro kinetic model
  • Medical device related infection

in vivo efficacy studies in murine infection models

  • Peritonitis/Sepsis
  • Thigh infection
  • Urinary tract infection
  • Skin infection
  • Pneumonia
  • Fungal sepsis

 

Last revised 21 December 2011

Contact

Department of Microbiological Surveillance and Research
Carina Vingsbo Lundberg, Ph.D
Senior Scientist, Head of Contract Research

Tel: +45 3268 8209