Gabriel Kristian Pedersen

Forskningsområder

Jeg forsker i, hvordan adjuvanser kan hjælpe vacciner til at yde optimal beskyttelse. Dette inkluderer:

• Undersøge hvordan forskellige vaccineadjuvanser virker
• Udvikle nye adjuvanssystemer
• Vaccinedesign og undersøgelse af hvilke adjuvanser som er bedst egnet ift. forskellige vaccinationsområder

Ansvarsområder

• Afsnitsleder for Vaccineadjuvanser, Afdeling for Infektionsimmunologi

Udvalgte publikationer

• Christensen D, Polacek C, Sheward DJ, Hanke L, Morro AM, McInerney G, Murrell B, Hartmann KT, Elvang Jensen H, Jungersen G, Illigen K, Isling LK, Jensen RF, Hansen JS, Rosenkrands I, Fernandez-Antunez C,  Ramirez S,  Follmann F, Bukh J, Pedersen GK. Protection against SARS-CoV-2 Transmission by a Parenteral Prime - Intranasal Boost Vaccine Strategy. eBioMedicine 2022 (in press)
• Van Haren SD*,Pedersen GK*, Kumar A, Ruckwardt TJ, Moin S, Moore IN, Minai M, Liu M, Pak J, Borriello F, Doss-Gollin S, Beijnen EMS, Ahmed S, Helmel M, Andersen P, Graham BS, Steen H, Christensen D, Levy O. CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns. Nat Comm 2022 (in press)
• Wørzner K, Sheward DJ, Schmidt ST, Hanke L, Zimmermann J, McInerney G, Karlsson Hedestam GB, Murrell B, Christensen D,Pedersen GK. Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice. EBioMedicine 2021;63:103197.
• Pedersen GK, Andersen P, Christensen D. 2018. Immunocorrelates of CAF family adjuvants. Semin Immunol 39: 4-13
• Pedersen GK, Àdori M, Khoenkhoen S, Dosenovic P, Beutler B, Karlsson Hedestam GB. 2014. B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS. PNAS 111:E4119-26